Search Thermo Fisher Scientific
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This peptide corresponds to 17 amino acids near the carboxy terminus of human MTERFD2.
PEP-1574 can be used as a blocking peptide with polyclonal antibody PA5-34531. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD2 is targeted to the mitochondria and is ubiquitously expressed, with highest expression levels in fore- and midbrain, diencephalon, spinal cord, tongue, lung liver and kidney. MTERFD2 has been suggested to play a role in organ differentiation during embryogenesis. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.
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Protein Aliases: Mitochondrial transcription termination factor 4; MTERF domain containing 2; mTERF domain-containing protein 2; Transcription termination factor 4, mitochondrial
Gene Aliases: HSPC096; MTERF4; MTERFD2
UniProt ID: (Human) Q7Z6M4
Entrez Gene ID: (Human) 130916
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