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This peptide corresponds to 12 amino acids near the carboxy terminus of human MYBPC1.
PEP-1383 can be used as a blocking peptide with polyclonal antibody PA5-34340.
Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the slow-type isoform designated MYBPC1. Both the fast-type (MYBPC2) and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. Multiple isoforms of MYBPC1 are known to exist, and are present in varying amounts in different skeletal muscles. It is thought that the MYBPC1 slow subfamily may play important roles in the assembly and stabilization of sarcomeric M- and A-bands and regulate the contractile properties of the actomyosin filaments.
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Protein Aliases: C-protein, skeletal muscle slow isoform; Myosin-binding protein C, slow-type; skeletal muscle C-protein; Slow MyBP-C
Gene Aliases: LCCS4; MYBPC1; MYBPCC; MYBPCS
UniProt ID: (Human) Q00872
Entrez Gene ID: (Human) 4604
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