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This peptide corresponds to 17 amino acid peptide near the center of human PRKCDBP.
PEP-1566 can be used as a blocking peptide with polyclonal antibody PA5-34523. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the "Signalosome", which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Caveolae-associated protein 3; Cavin-3; hSRBC; MGC20400; Protein kinase C delta-binding protein; protein kinase C, delta binding protein; sdr-related gene product that binds to c-kinase; Serum deprivation response factor-related gene product that binds to C-kinase
Gene Aliases: cavin-3; CAVIN3; HSRBC; PRKCDBP; SRBC
UniProt ID: (Human) Q969G5
Entrez Gene ID: (Human) 112464
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