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This peptide corresponds to 14 amino acids near the carboxy terminus of human RNF8.
PEP-1075 can be used as a blocking peptide with polyclonal antibody PA5-20961.
The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
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Protein Aliases: C3HC4-type zinc finger protein; E3 ubiquitin-protein ligase RNF8; FLJ12013; hRNF8; OTTHUMP00000039684; ring finger protein (C3HC4 type) 8; RING finger protein 8; ring finger protein 8, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase RNF8; UBC13/UEV-interacting ring finger protein
Gene Aliases: hRNF8; KIAA0646; RNF8
UniProt ID: (Human) O76064
Entrez Gene ID: (Human) 9025
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