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Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51629. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
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Protein Aliases: DNA-binding protein; Finger protein in nuclear bodies; hindsight homolog; Raf-responsive zinc finger protein LZ321; Ras-responsive element-binding protein 1; RREB 1; RREB-1; Zep 1; Zep-1; Zep1; zinc finger motif enhancer binding protein 1; Zinc finger motif enhancer-binding protein 1; zinc finger motif-enhancer binding-protein 1
Gene Aliases: FINB; HNT; LZ321; RREB-1; RREB1; Zep-1
UniProt ID: (Human) Q92766
Entrez Gene ID: (Human) 6239
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