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Invitrogen
Human SH3RF2 (aa 506-590) Control Fragment Recombinant Protein
Product Details
RP-103317
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
QGSLRKGRSSMRKNGSLQRPLQSGIPTLVVGSLRRSPTMVLRPQQFQFYQPQGIPSSPSAVVVEMGSKPALTGEPALTCISRGSE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (76%), Rat (76%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63527. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The SH3RF2 gene encodes a protein that has been shown to possess protein phosphatase 1 binding activity and ubiquitin protein ligase activity. This protein is involved in several cellular processes, including the positive regulation of the JNK cascade, protein autoubiquitination, and regulation of cellular protein metabolic processes. The protein is located in the nucleoplasm and mutations in the SH3RF2 gene have been associated with Ureter Transitional Cell Carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase SH3RF2; Heart protein phosphatase 1-binding protein; HEPP1; phosphatase 1 binding protein; POSH-eliminating RING protein; Protein phosphatase 1 regulatory subunit 39; protein phosphatase 1, regulatory subunit 39; RING finger protein 158; RING-type E3 ubiquitin transferase SH3RF2; SH3 domain-containing RING finger protein 2
Gene Aliases: HEPP1; POSH3; POSHER; PPP1R39; RNF158; SH3RF2
UniProt ID: (Human) Q8TEC5
Entrez Gene ID: (Human) 153769
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