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          • Proteins & Peptides ›
          • SLC35D1 Proteins

          Invitrogen

          Human SLC35D1 Synthetic Peptide

          View all (2) SLC35D1 proteins

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          Cite Human SLC35D1 Synthetic Peptide

          Additional Information:
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          Product Details

          PEP-0672

          Applications
          Tested Dilution
          Publications

          Neutralization (Neu)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Class

          Synthetic

          Type

          Peptide

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          200 µg/mL

          Purification

          purified

          Storage buffer

          PBS, pH 7.2, with 0.1% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Product Specific Information

          This peptide corresponds to 20 amino acids near the carboxy terminus of human Slc35D1.

          PEP-0672 can be used as a blocking peptide with polyclonal antibody PA5-20552.

          Target Information

          The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident Slc family member Slc35D1 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. These molecules can serve as substrates for chondroitin sulfate biosynthesis and mice lacking the Slc35D1 gene developed a lethal form of skeletal dysplasia with severe shortening of limbs and facial structures. Examination of epiphyseal cartilage in these mice revealed a decreased proliferating zone with round chrondrocytes, scarce matrices, and reduced proteoglycan aggregates. Loss of function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal dysplasia.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Nucleotide sugar transporter SLC35D1; solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1; solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1; Solute carrier family 35 member D1; UDP-galactose transporter-related 7; UDP-galactose transporter-related protein 7; UDP-GlcA/UDP-GalNAc transporter; UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter; UGTrel7

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          Gene Aliases: KIAA0260; SLC35D1; UGTREL7

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          UniProt ID: (Human) Q9NTN3

          View more View less

          Entrez Gene ID: (Human) 23169

          View more View less

          It has to be done as per old AB suggested Products section.
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