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Invitrogen
Human SNAPC3 (aa 34-129) Control Fragment Recombinant Protein
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Product Details
RP-105378
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
LPELNTRAFHVGAFGELWRGRLRGAGDLSLREPPASALPGSQAADSDREDAAVARDLDCSLEAAAELRAVCGLDKLKCLEDGEDPEVIPENTDLVT
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (74%), Rat (74%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66817. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Proximal sequence element-binding transcription factor subunit beta; PSE-binding factor subunit beta; PTF subunit beta; small nuclear RNA activating complex, polypeptide 3, 50kD; small nuclear RNA activating complex, polypeptide 3, 50kDa; Small nuclear RNA-activating complex polypeptide 3; SNAPc 50 kDa subunit; SNAPc subunit 3; snRNA-activating protein complex 50 kDa subunit; snRNA-activating protein complex subunit 3
Gene Aliases: PTFbeta; SNAP50; SNAPC3
UniProt ID: (Human) Q92966
Entrez Gene ID: (Human) 6619
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