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Invitrogen
Human STEAP4 Synthetic Peptide
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Product Details
PEP-0524
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 15 amino acids near the center of human STEAP4.
PEP-0524 can be used as a blocking peptide with polyclonal antibody PA5-20407.
Target Information
The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp666D049; FLJ23153; Metalloreductase STEAP4; six transmembrane prostate protein 2; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STEAP family member 4; Tumor necrosis factor, alpha-induced protein 9; tumor necrosis-alpha-induced adipose-related protein
Gene Aliases: STAMP2; STEAP4; TIARP; TNFAIP9
UniProt ID: (Human) Q687X5
Entrez Gene ID: (Human) 79689
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