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Invitrogen
Human TAS2R1 (aa 203-226) Control Fragment Recombinant Protein
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Product Details
RP-101452
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
RHTRQMRNTVAGSRVPGRGAPISA
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (42%), Rat (42%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62509. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The sense of taste is essential for the survival of organisms. For example, the ability to identify sweet-tasting foods enables animals to seek out food with high nutritive value, whereas the ability to identify bitter substances enables them to avoid the ingestion of potentially harmful substances. A family of integral membrane proteins are involved in taste perception and include T1R, which is involved in sweet taste perception and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. Specifically, T2R1 is expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC126778; MGC126780; T2R1; Taste receptor family B member 7; Taste receptor type 2 member 1; taste receptor, family B, member 7; taste receptor, type 2, member 1; TRB7
Gene Aliases: T2R1; TAS2R1; TRB7
UniProt ID: (Human) Q9NYW7
Entrez Gene ID: (Human) 50834
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