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Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (41%), Rat (41%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55845. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D1, also called TCTEX1 domain containing 1, belongs to the dynein light chain TCTEX-type family. Its function is still under investigation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dynein light chain Tctex-type 5; FLJ40873; MGC125768; Tctex1 domain-containing protein 1
Gene Aliases: DYNLT5; TCTEX1D1
UniProt ID: (Human) Q8N7M0
Entrez Gene ID: (Human) 200132
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