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Invitrogen
Human TCTEX1D4 Synthetic Peptide
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Product Details
PEP-1489
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 19 amino acids near the amino terminus of human TCTEX1D4.
PEP-1489 can be used as a blocking peptide with polyclonal antibody PA5-34447.
Target Information
Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D4, also called TCTEX2 beta, interacts with different members of the TGF-beta receptor family, and when overexpressed, inhibits TGF-beta signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dynein light chain Tctex-type 4; N22.1; novel Tctex-1 family domain-containing protein; Protein N22.1; Tctex-2-beta; Tctex1 domain-containing protein 4; Tctex2 beta
Gene Aliases: DYNLT4; TCTEX1D4
UniProt ID: (Human) Q5JR98
Entrez Gene ID: (Human) 343521
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