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Invitrogen
Human TLX2 Synthetic Peptide
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Product Details
PEP-1597
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 18 amino acid peptide near the amino terminus of human TLX2.
PEP-1597 can be used as a blocking peptide with polyclonal antibody PA5-34554. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37°C.
Target Information
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box 11-like 1; homeobox 11-like1; Homeobox protein Hox-11L1; Neural crest homeobox protein; T-cell leukemia homeobox protein 2
Gene Aliases: HOX11L1; NCX; TLX2
UniProt ID: (Human) O43763
Entrez Gene ID: (Human) 3196
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