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Product Details
PEP-0882
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Dry ice
Product Specific Information
This peptide corresponds to 17 amino acids near the carboxy terminus of human UCMA.
PEP-0882 can be used as a blocking peptide with polyclonal antibody PA5-20768.
Target Information
UCMA is a gene that encodes for a protein that is specific to chondrocytes and highly charged. This protein is expressed abundantly in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the protein has been associated with osteoarthritis in humans. Alternative splicing of the gene results in multiple transcript variants that encode different isoforms. UCMA is also associated with diseases such as Osteoarthritis and Poland Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gla-rich protein; Unique cartilage matrix-associated protein
Gene Aliases: C10orf49; GRP; GRP/UCMA; UCMA
UniProt ID: (Human) Q8WVF2
Entrez Gene ID: (Human) 221044
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