For maximum recovery please spin prior to use. Aliquoting the 5 µg, 10 µg, and 20 µg sizes of kinase is not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots; aliquots below 20 µL are not recommended. Never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
•Active-this protein can be used in kinase activity assays, such as Z’-LYTE™ assays, or in a binding assay platform like the LanthaScreen™ Eu Kinase Binding Assay (KBA).
•Purified-purity is determined by gel electrophoresis and provided in lot-specific certificate of analysis (COA).
•GST-tagged-provides animal origin flexibility. When used in the KBA platform, it can be paired with a goat- or rabbit-derived Eu-anti-GST antibody.
Protein Form: Full Length
YES1 is a recombinant human protein kinase that is a member of the SRC family of non-receptor tyrosine kinases and is the cellular homolog of the Yamaguchi sarcoma virus oncogene. It is involved in the regulation of cell growth and survival, including roles in apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: c-Src; cellular yes-1 protein; EC 22.214.171.124; p61-Yes; Proto-oncogene c-Yes; proto-oncogene tyrosine-protein kinase YES; Tyrosine-protein kinase Yes; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1; Yamaguchi sarcoma oncogene; YES1 proto-oncogene, Src family tyrosine kinase
Gene Aliases: c-yes; HsT441; P61-YES; YES; YES1
UniProt ID: (Human) P07947
Entrez Gene ID: (Human) 7525