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Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; desmosomal protein 3; Junction plakoglobin; OTTHUMP00000164735
Gene Aliases: CTNNG; DP3; DPIII; JUP; PDGB; PG; PKGB
UniProt ID: (Human) P14923
Entrez Gene ID: (Human) 3728
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