Product References
Notch-Regulated Dendritic Cells Restrain Inflammation-Associated Colorectal Carcinogenesis.
Cancer immunology research
Wang L,Yu S,Chan ER,Chen KY,Liu C,Che D,Awadallah A,Myers J,Askew D,Huang AY,Maillard I,Huang D,Xin W,Zhou L
250-07 was used in Sample Preparation (FC/FACS) to study the significance of Notch-regulated dendritic cell (DC) immune responses in a mouse model of colitis-associated colorectal cancer in which there is epithelial downregulation of Notch/Hes1 signaling.
Mon Mar 01 00:00:00 EST 2021
Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors.
Cell reports
Uzhachenko RV,Bharti V,Ouyang Z,Blevins A,Mont S,Saleh N,Lawrence HA,Shen C,Chen SC,Ayers GD,DeNardo DG,Arteaga C,Richmond A,Vilgelm AE
Tue Apr 06 00:00:00 EDT 2021
Neddylation pathway alleviates chronic pancreatitis by reducing HIF1α-CCL5-dependent macrophage infiltration.
Cell death & disease
Lin Y,Chen Y,Feng W,Hua R,Zhang J,Huo Y,Jiang H,Yin B,Yang X
Mon Mar 15 00:00:00 EDT 2021
Aging-induced IL27Ra signaling impairs hematopoietic stem cells.
Blood
He H,Xu P,Zhang X,Liao M,Dong Q,Cong T,Tang B,Yang X,Ye M,Chang Y,Liu W,Wang X,Ju Z,Wang J
Thu Jul 09 00:00:00 EDT 2020
Cytotoxic T cells swarm by homotypic chemokine signalling.
eLife
Galeano Niño JL,Pageon SV,Tay SS,Colakoglu F,Kempe D,Hywood J,Mazalo JK,Cremasco J,Govendir MA,Dagley LF,Hsu K,Rizzetto S,Zieba J,Rice G,Prior V,O'Neill GM,Williams RJ,Nisbet DR,Kramer B,Webb AI,Luciani F,Read MN,Biro M
Tue Oct 13 00:00:00 EDT 2020
CCL5 secreted by senescent theca-interstitial cells inhibits preantral follicular development via granulosa cellular apoptosis.
Journal of cellular physiology
Shen L,Chen Y,Cheng J,Yuan S,Zhou S,Yan W,Liu J,Luo A,Wang S
250-07 was used in In vitro experiments to suggest that SASP-associated CCL5 produced by senescent theca-interstitial cells may impair follicle development and maturation during ovarian aging by promoting granulosa cell apoptosis.
Sun Dec 01 00:00:00 EST 2019
MicroRNA-155 Modulates Acute Graft-versus-Host Disease by Impacting T Cell Expansion, Migration, and Effector Function.
Journal of immunology (Baltimore, Md. : 1950)
Zitzer NC,Snyder K,Meng X,Taylor PA,Efebera YA,Devine SM,Blazar BR,Garzon R,Ranganathan P
Fri Jun 15 00:00:00 EDT 2018
Human Binge Alcohol Intake Inhibits TLR4-MyD88 and TLR4-TRIF Responses but Not the TLR3-TRIF Pathway: HspA1A and PP1 Play Selective Regulatory Roles.
Journal of immunology (Baltimore, Md. : 1950)
Muralidharan S,Lim A,Catalano D,Mandrekar P
Sun Apr 01 00:00:00 EDT 2018
Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
Nature communications
Xu Y,Ikeda S,Sumida K,Yamamoto R,Tanaka H,Minato N
Fri Mar 02 00:00:00 EST 2018
Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α.
Nature communications
Wang Q,He Z,Huang M,Liu T,Wang Y,Xu H,Duan H,Ma P,Zhang L,Zamvil SS,Hidalgo J,Zhang Z,O'Rourke DM,Dahmane N,Brem S,Mou Y,Gong Y,Fan Y
Thu Feb 08 00:00:00 EST 2018
Modulation of double-stranded RNA pattern recognition receptor signaling in ovarian cancer cells promotes inflammatory queues.
Oncotarget
Muccioli M,Nandigam H,Loftus T,Singh M,Venkatesh A,Wright J,Pate M,McCall K,Benencia F
250-07 was used in Enzyme-linked immunosorbent assay to investigate the potential of mouse and human ovarian cancer cells to produce inflammatory factors in response to pathogen recognition receptor signalling.
Fri Nov 30 00:00:00 EST 2018
CCL5 Promotes Resolution-Phase Macrophage Reprogramming in Concert with the Atypical Chemokine Receptor D6 and Apoptotic Polymorphonuclear Cells.
Journal of immunology (Baltimore, Md. : 1950)
Aswad M,Assi S,Schif-Zuck S,Ariel A
Tue Aug 15 00:00:00 EDT 2017
Platelets Mediate Host Defense against Staphylococcus aureus through Direct Bactericidal Activity and by Enhancing Macrophage Activities.
Journal of immunology (Baltimore, Md. : 1950)
Ali RA,Wuescher LM,Dona KR,Worth RG
Sun Jan 01 00:00:00 EST 2017
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
Scientific reports
Singh K,Davies G,Alenazi Y,Eaton JRO,Kawamura A,Bhattacharya S
Tue Jun 27 00:00:00 EDT 2017
Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.
Scientific reports
Yagawa Y,Robertson-Tessi M,Zhou SL,Anderson ARA,Mulé JJ,Mailloux AW
Wed Nov 22 00:00:00 EST 2017
C-C Chemokine Ligand-5 is critical for facilitating macrophage infiltration in the early phase of liver ischemia/reperfusion injury.
Scientific reports
Lee CM,Peng HH,Yang P,Liou JT,Liao CC,Day YJ
250-07 was used in In vivo experiments to investigate CCL5 in hepatic ischemia/reperfusion injury.
Fri Jun 16 00:00:00 EDT 2017
Hepatocyte Growth Factor Receptor c-Met Instructs T Cell Cardiotropism and Promotes T Cell Migration to the Heart via Autocrine Chemokine Release.
Immunity
Komarowska I,Coe D,Wang G,Haas R,Mauro C,Kishore M,Cooper D,Nadkarni S,Fu H,Steinbruchel DA,Pitzalis C,Anderson G,Bucy P,Lombardi G,Breckenridge R,Marelli-Berg FM
Tue Jun 16 00:00:00 EDT 2015
CCR6-dependent positioning of memory B cells is essential for their ability to mount a recall response to antigen.
Journal of immunology (Baltimore, Md. : 1950)
Elgueta R,Marks E,Nowak E,Menezes S,Benson M,Raman VS,Ortiz C,O'Connell S,Hess H,Lord GM,Noelle R
Thu Jan 15 00:00:00 EST 2015
Primary Macrophage Chemotaxis Induced by Cannabinoid Receptor 2 Agonists Occurs Independently of the CB2 Receptor.
Scientific reports
Taylor L,Christou I,Kapellos TS,Buchan A,Brodermann MH,Gianella-Borradori M,Russell A,Iqbal AJ,Greaves DR
Tue Jun 02 00:00:00 EDT 2015
Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens.
The Journal of biological chemistry
Bufe B,Schumann T,Kappl R,Bogeski I,Kummerow C,Podgórska M,Smola S,Hoth M,Zufall F
Fri Mar 20 00:00:00 EDT 2015
RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling.
Nature communications
Patel J,McNeill E,Douglas G,Hale AB,de Bono J,Lee R,Iqbal AJ,Regan-Komito D,Stylianou E,Greaves DR,Channon KM
Wed Mar 18 00:00:00 EDT 2015
Hydrodynamic Gene Delivery of CC Chemokine Binding Fc Fusion Proteins to Target Acute Vascular Inflammation In Vivo.
Scientific reports
McNeill E,Iqbal AJ,White GE,Patel J,Greaves DR,Channon KM
Tue Dec 01 00:00:00 EST 2015
Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs.
The Journal of cell biology
Liou GY,Döppler H,Necela B,Krishna M,Crawford HC,Raimondo M,Storz P
Mon Aug 05 00:00:00 EDT 2013
IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection.
Journal of immunology (Baltimore, Md. : 1950)
Gwyer Findlay E,Villegas-Mendez A,de Souza JB,Inkson CA,Shaw TN,Saris CJ,Hunter CA,Riley EM,Couper KN
Wed May 01 00:00:00 EDT 2013
Aurintricarboxylic acid ameliorates experimental autoimmune encephalomyelitis by blocking chemokine-mediated pathogenic cell migration and infiltration.
Journal of immunology (Baltimore, Md. : 1950)
Zhang F,Wei W,Chai H,Xie X
Fri Feb 01 00:00:00 EST 2013
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
The Journal of experimental medicine
Yang D,Postnikov YV,Li Y,Tewary P,de la Rosa G,Wei F,Klinman D,Gioannini T,Weiss JP,Furusawa T,Bustin M,Oppenheim JJ
Mon Jan 16 00:00:00 EST 2012
Chemokine receptor Ccr1 drives neutrophil-mediated kidney immunopathology and mortality in invasive candidiasis.
PLoS pathogens
Lionakis MS,Fischer BG,Lim JK,Swamydas M,Wan W,Richard Lee CC,Cohen JI,Scheinberg P,Gao JL,Murphy PM
Mon Dec 17 00:00:00 EST 2012
Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth.
Journal of immunology (Baltimore, Md. : 1950)
Schlecker E,Stojanovic A,Eisen C,Quack C,Falk CS,Umansky V,Cerwenka A
Sat Dec 15 00:00:00 EST 2012
Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis.
The Journal of experimental medicine
de Jager SC,Bermúdez B,Bot I,Koenen RR,Bot M,Kavelaars A,de Waard V,Heijnen CJ,Muriana FJ,Weber C,van Berkel TJ,Kuiper J,Lee SJ,Abia R,Biessen EA
Mon Feb 14 00:00:00 EST 2011
An aberrant thymus in CCR5-/- mice is coupled with an enhanced adaptive immune response in fungal infection.
Journal of immunology (Baltimore, Md. : 1950)
Kroetz DN,Deepe GS
Sun May 15 00:00:00 EDT 2011
CCL5 neutralization restricts cancer growth and potentiates the targeting of PDGFRβ in colorectal carcinoma.
PloS one
Cambien B,Richard-Fiardo P,Karimdjee BF,Martini V,Ferrua B,Pitard B,Schmid-Antomarchi H,Schmid-Alliana A
Mon Apr 23 00:00:00 EDT 2012
Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4.
The Journal of experimental medicine
Janas ML,Varano G,Gudmundsson K,Noda M,Nagasawa T,Turner M
Mon Jan 18 00:00:00 EST 2010
Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection.
PLoS pathogens
Crawford MA,Burdick MD,Glomski IJ,Boyer AE,Barr JR,Mehrad B,Strieter RM,Hughes MA
Thu Nov 18 00:00:00 EST 2010
Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity.
Journal of immunology (Baltimore, Md. : 1950)
Arthur JC,Lich JD,Ye Z,Allen IC,Gris D,Wilson JE,Schneider M,Roney KE,O'Connor BP,Moore CB,Morrison A,Sutterwala FS,Bertin J,Koller BH,Liu Z,Ting JP
Fri Oct 15 00:00:00 EDT 2010
A cell-impermeable cyclosporine A derivative reduces pathology in a mouse model of allergic lung inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Balsley MA,Malesevic M,Stemmy EJ,Gigley J,Jurjus RA,Herzog D,Bukrinsky MI,Fischer G,Constant SL
Wed Dec 15 00:00:00 EST 2010
Pan-CC chemokine neutralization restricts splenocyte egress and reduces inflammation in a model of arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Buatois V,Fagète S,Magistrelli G,Chatel L,Fischer N,Kosco-Vilbois MH,Ferlin WG
Sun Aug 15 00:00:00 EDT 2010
CCR5 expression levels influence NFAT translocation, IL-2 production, and subsequent signaling events during T lymphocyte activation.
Journal of immunology (Baltimore, Md. : 1950)
Camargo JF,Quinones MP,Mummidi S,Srinivas S,Gaitan AA,Begum K,Jimenez F,VanCompernolle S,Unutmaz D,Ahuja SS,Ahuja SK
Thu Jan 01 00:00:00 EST 2009
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.
Journal of immunology (Baltimore, Md. : 1950)
Izhak L,Wildbaum G,Zohar Y,Anunu R,Klapper L,Elkeles A,Seagal J,Yefenof E,Ayalon-Soffer M,Karin N
Wed Jul 01 00:00:00 EDT 2009
The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections.
Immunity
Kohlmeier JE,Miller SC,Smith J,Lu B,Gerard C,Cookenham T,Roberts AD,Woodland DL
Fri Jul 18 00:00:00 EDT 2008
Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.
Cell stem cell
Di Giorgio FP,Boulting GL,Bobrowicz S,Eggan KC
Thu Dec 04 00:00:00 EST 2008
CXCL10 blockade protects mice from cyclophosphamide-induced cystitis.
Journal of immune based therapies and vaccines
Sakthivel SK,Singh UP,Singh S,Taub DD,Novakovic KR,Lillard JW
Tue Oct 28 00:00:00 EDT 2008
Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate.
Blood
Howard OM,Dong HF,Su SB,Caspi RR,Chen X,Plotz P,Oppenheim JJ
Wed Jun 01 00:00:00 EDT 2005
Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease.
Blood
Wysocki CA,Jiang Q,Panoskaltsis-Mortari A,Taylor PA,McKinnon KP,Su L,Blazar BR,Serody JS
Tue Nov 01 00:00:00 EST 2005
Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors.
The Journal of experimental medicine
Weller CL,Collington SJ,Brown JK,Miller HR,Al-Kashi A,Clark P,Jose PJ,Hartnell A,Williams TJ
Mon Jun 20 00:00:00 EDT 2005
CCR1 and CC chemokine ligand 5 interactions exacerbate innate immune responses during sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Ness TL,Carpenter KJ,Ewing JL,Gerard CJ,Hogaboam CM,Kunkel SL
Wed Dec 01 00:00:00 EST 2004
Hematopoietic stem cells are uniquely selective in their migratory response to chemokines.
The Journal of experimental medicine
Wright DE,Bowman EP,Wagers AJ,Butcher EC,Weissman IL
Mon May 06 00:00:00 EDT 2002
The intestinal chemokine thymus-expressed chemokine (CCL25) attracts IgA antibody-secreting cells.
The Journal of experimental medicine
Bowman EP,Kuklin NA,Youngman KR,Lazarus NH,Kunkel EJ,Pan J,Greenberg HB,Butcher EC
Mon Jan 21 00:00:00 EST 2002
Homeostatic T cell proliferation in a T cell-dendritic cell coculture system.
Proceedings of the National Academy of Sciences of the United States of America
Ge Q,Palliser D,Eisen HN,Chen J
Tue Mar 05 00:00:00 EST 2002
CCL7 and CXCL10 orchestrate oxidative stress-induced neutrophilic lung inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Michalec L,Choudhury BK,Postlethwait E,Wild JS,Alam R,Lett-Brown M,Sur S
Tue Jan 15 00:00:00 EST 2002
Developmental switches in chemokine response profiles during B cell differentiation and maturation.
The Journal of experimental medicine
Bowman EP,Campbell JJ,Soler D,Dong Z,Manlongat N,Picarella D,Hardy RR,Butcher EC
Mon Apr 17 00:00:00 EDT 2000