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210-12P80H-100UG will be provided as 2 x 50 µg (210-12P80H-50UG).
210-12P80H-1MG will be provided as 20 x 50 µg (210-12P80H-50UG).
210-12P80H-250UG will be provided as 5 x 50 µg (210-12P80H-50UG).
210-12P80H-500UG will be provided as 5 x 100 µg (210-12P80H-50UG).
Recombinant Murine IL-12 p80 is an 80.0 kDa, disulfide linked homodimer of two p40 chains of IL-12 that consists of 626 amino acid residues and less than 5% of the IL-12 p40 monomer.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
IL-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicates that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23, or it can form the homodimer designated IL-12 p80. Elevated levels of IL-12 p80 correlate to macrophage recruitment and increased inflammation in asthma and respiratory viral infection models.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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