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Invitrogen
Mouse TPO (Thrombopoietin) Recombinant Protein
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Product Details
RP-87910
Product Specifications
Expression System
CHO cells
Class
Recombinant
Type
Protein
Conjugate
Form
Liquid
Concentration
200 µg/mL
Amount
25 µg
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Carrier-Free
Stock solutions can also be prepared at 50 - 100 µg/mL in appropriate sterile buffer, carrier protein such as 0.2 - 1% BSA or HSA can be added when preparing the stock solution.
Target Information
Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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