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Invitrogen
RecQ DNA Helicase Recombinant Protein
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Product Details
RP-4902
Product Specifications
Expression System
E. coli
Class
Recombinant
Type
Protein
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
20 µg
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
Product Specific Information
RP-4902 can be used as a positive control as well as in studies on mechanisms of DNA recombination, replication and repair.
RP-4902 calculated molecular weight is ~64 kDa. Purity is greater than 90%.
Upon arrival, centrifuge briefly and store at -20°C or -80°C for longer periods.
Target Information
E. coli RecQ helicase contributes to the genomic stability as the prototype of RecQ family DNA helicases, mutations of which genes are associated with premature aging and cancer susceptibility, known as Bloom's and Werner's syndromes. RecQ helicase functions in both early and late stages of homologous recombination and unwinds DNA with particular structures, such as the fork structure for replication, the Holliday junction which is an intermediate of recombination, telomere, quadruplex G4-DNA, etc. In replication fork, it forms a complex with topoisomerase III and regulates DNA topology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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