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RP-4903 can be used as a positive control for Western blots, as well as in studies on mechanisms of DNA recombination, replication and repair.
RP-4903 calculated molecular weight is ~64 kDa.
E. coli RecQ helicase contributes to the genomic stability as the prototype of RecQ family DNA helicases, mutations of which genes are associated with premature aging and cancer susceptibility, known as Bloom's and Werner's syndromes. RecQ helicase functions in both early and late stages of homologous recombination and unwinds DNA with particular structures, such as the fork structure for replication, the Holliday junction which is an intermediate of recombination, telomere, quadruplex G4-DNA, etc. In replication fork, it forms a complex with topoisomerase III and regulates DNA topology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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