CD2BP2 Proteins

Protein Information

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.

Synonyms

1500011B02Rik; 2410024K20Rik; AW048183; CD2 (cytoplasmic tail) binding protein 2; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 cytoplasmic tail binding protein 2; CD2 tail-binding protein 2; CD2BP2; FWP010; KIAA1178; LIN1; PPP1R59; protein phosphatase 1, regulatory subunit 59; Snu40; U5 snRNP 52K protein; U5-52K