COX5A Proteins

Protein Information

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22.

Synonyms

AA959768; CcOX; COX; Cox5a; COX5A protein; COX-VA; cytochrome c oxidase polypeptide Va; cytochrome c oxidase polypeptide, mitochondrial; cytochrome c oxidase subunit 5A; cytochrome c oxidase subunit 5A, mitochondrial; cytochrome c oxidase subunit Va; cytochrome c oxidase, subunit Va; mitochondrial cytochrome c oxidase subunit 5a; mitochondrial cytochrome c oxidase subunit Va; VA