DCD Proteins

Protein Information

DCD is a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.

Synonyms

AIDD; DCD; DCD-1; Dermcidin; diffusible survival/evasion peptide; DSEP; HCAP; PIF; Preproteolysin; proteolysis inducing factor; survival promoting peptide; Survival-promoting peptide