FABP3 Proteins

Protein Information

Fatty acid binding proteins (FABP) are small (approximately 13-14 kDa) intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long chain fatty acids. They are abundantly present in various cell types and seem to play an important role in the intracellular utilization of fatty acids. There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks, due to its small size, rapidly out of is chemically damaged dying cells leading to a rise in serum levels. Liver FABP is a sensitive marker for cell damage of liver cells in vitro and in vivo. Is chemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. Next to this L FABP is a marker for rapid hepatocyte lysis in vitro (as for example in toxicology assays) and for detection of liver damage during and after transplantation.

Synonyms

422 protein; Cardiac Fatty Acid Binding Protein; FABP 3; FABP11; Fabp3; Fabph1; Fabph-1; Fabph4; Fabph-4; fatty acid binding protein 11; fatty acid binding protein 3; Fatty acid binding protein 3 heart; fatty acid binding protein 3, muscle and heart; Fatty acid binding protein heart; fatty acid binding protein heart 1; fatty acid binding protein heart 4; fatty acid-binding protein 3; Fatty acid-binding protein, heart; heart FABP; heart fatty acid binding protein; Heart type fatty acid binding protein; heart-type fatty acid-binding protein; H-FABP; M FABP; Mammary derived growth inhibitor; Mammary-derived growth inhibitor; MDGI; M-FABP; muscle and heart (mammary derived growth inhibitor); Muscle fatty acid binding protein; Muscle fatty acid-binding protein; Muscle O-FABP; Mylein protein P2 homolog / adopocyte; O-FABP