FRY Proteins

Protein Information

The FRY gene encodes a protein known as furry homolog (FRY), a gene that is highly conserved across species and plays vital roles in cell division and differentiation. FRY is involved in the regulation of mitotic spindle orientation and cellular polarity, crucial for proper cell division and tissue organization. It is found within various tissues and has implications in neurodevelopment and cancer biology, where it influences cell structural properties and signaling pathways. Alterations in FRY expression or mutations can disrupt normal cell function, leading to aberrant cellular morphogenesis and developmental defects. In cancer studies, FRY is associated with tumor suppression, where loss of function contributes to uncontrolled cell proliferation. This gene interacts with other cellular components, such as the cytoskeleton and signaling proteins, orchestrating complex cellular processes essential for maintaining homeostasis and development.

Synonyms

13CDNA73; 214K23.2; bA207N4.2; bA37E23.1; C13orf14; CG003; FRY; FRY microtubule binding protein; furry homolog; protein furry homolog; WUGSC:H_2G3A.1