IGHMBP2 Proteins

Protein Information

5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation. DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV.

Synonyms

AEP; antifreeze enhancer-binding protein; antifreeze enhancer-binding protein ortholog; ATP-dependent helicase IGHMBP2; cardiac transcription factor 1; CATF1; CMT2S; DNA-binding protein SMUBP-2; GF-1; Glial factor 1; HCSA; HMN6; Ighmbp2; immunoglobulin mu binding protein 2; immunoglobulin mu DNA binding protein 2; immunoglobulin mu-binding protein 2; immunoglobulin S mu binding protein 2; neuromuscular degeneration; nmd; p110 subunit; RIPE3b1; sma; SMARD1; Smbp2; Smbp-2; SMUBP2; ZFAND7; zinc finger, AN1-type domain 7