P2Y1 Proteins

Protein Information

P2Y1 is a Purinergic Receptor that causes a change in platelet shape and potentially leads to platelet aggregation by binding ADP, which results in the mobilization of intracellular calcium ions via activation of phospholipase C. This receptor also mediates the release of the relaxing factor nitric oxide and may be involved in the modulation of neuronal signal transmission. P2Y1 has been reported to be expressed in tissues throughout the body, particularly brain. ESTs have been isolated from human embryo, lung, and placenta libraries.

Synonyms

ADP receptor; ATP receptor; P2 purinoceptor subtype Y1; P2 purinoreceptor subclass 2Y; P2RY1; P2y; P2Y ATP receptor 1; P2Y purinoceptor 1; P2Y1; P2Y1 receptor; p2y1r; p2y-1-r; platelet ADP receptor; Purinergic receptor; purinergic receptor P2Y, G-protein coupled 1; purinergic receptor P2Y, G-protein coupled, 1; purinergic receptor P2Y1; Purinoceptor p2y1; Purinoceptor p2yr1