PDC Proteins

Protein Information

PDC encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. PDC is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms

33 kDa phototransducing protein; 33DPTP; G beta gamma binding protein; MEKA; MEKA protein; Pdc; PHD; PhLOP; PhLP; Phosducin; phosducin-like orphan protein; Phototransducing protein, 33 kDa (phosducin); Protein MEKA; Rod photoreceptor 1; Rpr1; RPR-1