S100A6 Proteins

Protein Information

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Synonyms

2A9; 5B10; CABP; Cacy; calcium binding protein A6 (calcyclin); calcyclin; Growth factor-inducible protein 2A9; lung 10 kDa protein; MLN 4; PRA; Prolactin receptor-associated protein; protein S100-A6; S100 calcium binding protein A6; S100 calcium binding protein A6 (calcyclin); S100 calcium-binding protein A6; S100 calcium-binding protein A6 (calcyclin); S100a6