SFTPD Proteins

Protein Information

Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.

Synonyms

AI573415; COLEC7; Collectin7; collectin-7; CP4; EGK_19692; Lung surfactant protein D; PSPD; PSP-D; PSP-D Surfactant protein D; pulmonary surfactant apoprotein; Pulmonary surfactant associated protein PSP-D; pulmonary surfactant protein D; pulmonary surfactant-associated protein D; SFTP 4; Sftp4; SFTPD; SPD; SP-D; surfactant associated protein D; Surfactant associated protein pulmonary 4; surfactant protein D; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4