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          • Proteins & Peptides ›
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          SIK2 Proteins

          SIK2 Human peptides and recombinant proteins are validated for use in the following applications: Neutralization and Kinase Assay. These proteins are expressed in E. coli and Insect cells. Available Product Grades: Research Use Only. Browse all 4 proteins. Not finding the exact protein, grade or... SIK2 Human peptides and recombinant proteins are validated for use in the following applications: Neutralization and Kinase Assay. These proteins are expressed in E. coli and Insect cells. Available Product Grades: Research Use Only. Browse all 4 proteins. Not finding the exact protein, grade or size needed?... SIK2 Human peptides and recombinant proteins are validated for use in the following applications: Neutralization and Kinase Assay. These proteins are expressed in E. coli and Insect cells. Available Product Grades: Research Use Only. Browse all 4 proteins. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... SIK2 Human peptides and recombinant proteins are validated for use in the following applications: Neutralization and Kinase Assay. These proteins are expressed in E. coli and Insect cells. Available Product Grades: Research Use Only. Browse all 4 proteins. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

          Protein Information

          SNF1LK2 (QIK) is a serine/threonine kinase and is a salt-inducible kinase that belongs to the AMP-activated protein kinase family. SNF1LK2 negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1'alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.

          Synonyms

          G630080D20Rik; KIAA0781; LOH11CR1I; QIK; Qin-induced kinase; RGD1559698; salt induceable kinase 2; salt inducible kinase 2; salt-inducible kinase 2; salt-inducible protein kinase 2; salt-inducible serine/threonine kinase 2; serine/threonine-protein kinase SIK2; Serine/threonine-protein kinase SNF1-like kinase 2; Sik2; SIK-2; SNF1-like kinase 2; SNF1LK2

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Invitrogen
          Human SNF1LK2, GST Tag Recombinant Protein
          Invitrogen
          Human SNF1LK2, GST Tag Recombinant Protein
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          Human
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          Insect cells
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          Research Use Only
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          Cat # PV4792

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