SPTBN1 Proteins

Protein Information

Spectrin (Sp), the most abundant of the erythrocyte membrane skeleton proteins, helps these cells maintain their characteristic biconcave shape while remaining flexible and elastic. Erythrocyte Sp is a heterodimer composed of a 280 kDa alpha subunit and a 246 kDa beta subunit which associate in a side-to-side, antiparallel configuration to form a 100 nm rod-like structure. Sp in other tissues may be composed of distinct but homologous alpha and beta subunits, sometimes referred to as fodrin. A newly introduced nomenclature designates the Sp subunits of the erythrocyte as alpha-1 and beta-1, and the fodrin subunits as alpha-2 and beta-2. Alternatively spliced forms of each are designated as epsilon-1, epsilon-2, etc. (e. g. beta-1 epsilon-1).

Synonyms

9930031C03Rik; A2a; a--fodrin; AI842465; AL033301; alpha II spectrin; alpha-fodrin; alpha-II spectrin; alpha-spectrin 2; beta fodrin; beta II spectrin-like (short form); beta-fodrin; beta-G spectrin; beta-I spectrin; Beta-II spectrin; beta-spectrin 1; beta-spectrin 2; beta-spectrin 2, non-erythrocytic; beta-spectrin II; beta-spectrin non-erythrocytic 1; betaSpII; brain alpha-spectrin; brain erythroid spectrin (235E); brain spectrin; bSPII-; cytoskeleton protein; D330027P03Rik; EL3; ELF; elf1; elf3; embryonic liver beta-fodrin; embryonic liver fodrin; embryonic liver fodrin beta chain; epididymis luminal protein 102; erythroid spectrin beta; fodrin alpha chain; Fodrin beta chain; Gm1301; HEL102; HS2; HSPTB1; inhibitory protein factor; IPF; ja; jaundiced; membrane cytoskeletal protein; mKIAA4049; mKIAA4219; noerythroid alpha-spectrin 2; non-erythrocytic; nonerythroid alpha-spectrin 2; non-erythroid spectrin beta; short form of beta II spectrin; Sp beta; spectrin alpha chain, brain; spectrin alpha chain, non-erythrocytic 1; spectrin beta 1; spectrin beta 2; spectrin beta chain, brain 1; spectrin beta chain, erythrocyte; spectrin beta chain, erythrocytic; Spectrin beta chain, non-erythrocytic 1; spectrin beta Tandil; spectrin beta, erythrocytic; spectrin beta, non-erythrocytic 1; spectrin G; spectrin R; spectrin, alpha, non-erythrocytic 1; spectrin, beta, erythrocytic; spectrin, beta, non-erythrocytic 1; spectrin, non-erythroid alpha chain; spectrin, non-erythroid beta chain 1; SPH2; Spna2; Spnb1; Spnb-1; Spnb2; Spnb-2; Spta2; Sptan1; SPTB; SPTB1; Sptb2; Sptbn1