XK Proteins

Protein Information

The XK protein is a membrane-bound protein associated with the endoplasmic reticulum (ER) and forms part of the ER membrane complex (EMC), which is critical for various cellular processes. This protein is involved in the insertion, folding, and assembly of membrane proteins in eukaryotic cells. The XK protein's role in the ER highlights its importance in maintaining proper cell function, as the ER is integral in protein synthesis, lipid metabolism, and calcium storage. Furthermore, the XK protein's involvement in these processes underscores its significance in cellular homeostasis and its potential contribution to pathologies when mutated or dysfunctional.

Synonyms

1810038K19Rik; Kell blood group precursor (McLeod phenotype); Kell blood group precursor (McLeod phenotype) homolog; kell complex 37 kDa component; KX; Kx antigen; MCLDS; McLeod syndrome gene homolog; membrane transport protein XK; NA; NAC; neuroacanthocytosis; neurocanthocytosis; X1k; Xk; XK homolog; XK, Kell blood group complex subunit (McLeod syndrome); Xkh; XKR1; XK-related protein 1; X-linked Kx blood group; X-linked Kx blood group (McLeod syndrome); X-linked Kx blood group (McLeod syndrome) homolog; Xrg1