Digital PCR for Liquid Biopsy

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Liquid biopsy enables non-invasive biomarker testing to identify and track oncogenic mutations. It can detect and monitor cancer through the analysis of circulating tumor DNA (ctDNA) and other biomarkers found in blood or other bodily fluids. Digital PCR (dPCR) can enhance liquid biopsy research by providing highly sensitive and precise quantification of DNA and RNA molecules, enabling the detection of low-abundance genetic mutations and variations, the tracking of tumor dynamics, and assessment of minimal residual disease.

Liquid biopsy resources

Webinar: dPCR enables precise quantification of ctDNA from liquid biopsies

Characterizing ctDNA helps researchers detect cancer early, measure therapeutic response, quantify residual tumor burden, and monitor emerging resistance to potential therapies. Because ctDNA fragments are typically short and very low in concentration, the sensitivity of dPCR makes it an ideal tool for ctDNA studies.

Flyer: Absolute Q dPCR assays for liquid biopsy

Absolute Q Liquid Biopsy dPCR assays enable reproducible, specific detection of known somatic mutations. Each predesigned assay has been validated using controls to detect down to 0.1% variant allele frequency in genes relevant for cancer research.

 

Absolute Q Liquid Biopsy dPCR assays are:

  • Simple—preformulated and verified assay in a single tube, enabling you to immediately start your research
  • Fast—minimal hands-on time; results in 90 minutes when used with the QuantStudio Absolute Q Digital PCR System
  • Highly sensitive—detect down to 0.1% variant allele frequency
  • Robust—analyze your data with confidence using verified assays backed by a performance guarantee

Poster: Implementation of digital PCR TaqMan multiplex assay enables high sensitivity for detection of ESR1 mutations in liquid biopsy material

Order assays

To order Absolute Q Liquid Biopsy dPCR Assays, indicate the desired quantity in the appropriate assay row, then scroll to the bottom of the table and click 'Add to cart'. Follow the in-cart instructions to complete your purchase.

For Research Use Only. Not for use in diagnostic procedures.