Ambient ionization mass spectrometry techniques that enable direct, gentle, and rapid analysis of samples offer exciting opportunities to provide clinicians with rich molecular data to enhance decision-making. Here, an overview of several ongoing clinical projects in the Eberlin laboratory related to the development of a handheld MS-based device, the MasSpec Pen technology, for improving patient care will be discussed. In particular, I will describe results centered around our efforts in employing the MasSpec Pen for intraoperative tissue analysis and cancer detection, identification of infectious microorganisms, and detection of drugs of abuse. Current challenges and opportunities towards incorporating this technology into clinical practice will also be addressed.

For Research Use Only. Not for use in diagnostic procedures.

About the presenter

Mary King, PhD Candidate, Prof. Livia S. Eberlin Group The University of Texas at Austin

Mary King, PhD Candidate – Prof. Livia S. Eberlin Group The University of Texas at Austin

Mary received her Bachelor’s of Science in Chemistry at Mississippi State University in 2017 where she worked on analytical chemistry research related to environmental conservation as well as nanomaterial characterization. After graduating with her bachelor’s degree, she joined the laboratory of Prof. Livia Eberlin at The University of Texas at Austin where she is currently a PhD candidate. Her main research focuses on developing and applying ambient ionization mass spectrometry-based tools for in vivo cancer diagnosis and lipid biomarker discovery.

 
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