Oral Fluid and Breath Drug Testing

Convenient and innovative sample matrices

Forensic labs are validating new biological matrices to make sample collection and testing more convenient and reliable than ever. Among the advances are less invasive collection (without the need for medical personnel), and roadside or immediate sampling—all while maintaining sample integrity and chain of custody.

Cutting edge analytical technology has allowed forensic toxicologists to reliably identify and quantify drugs of abuse in alternative matrices such as oral fluid and exhaled breath. Both of these matrices show promise for addressing the complications of traditional sample collection, provide reliable and accurate results, and benefit from improved MS technology such as high-resolution accurate mass (HRAM) Orbitrap MS and the latest tandem MS (MS/MS).

Featured oral fluid and breath drug testing resources

Application note

Analyzing THC and THCCOOH in oral fluid using triple quadrupole LC-MS/MS

Discover tomorrow’s drugs today with high-resolution Orbitrap mass spectrometry, routinely selected first by researchers.

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Simultaneous quantification of several major and minor cannabinoids in oral fluid using high resolution accurate mass Orbitrap MS


Exhaled Breath Analysis Becomes Easier for more Reliable Drugs of Abuse Testing

Exhaled breath is an attractive biomatrix for forensic toxicology. Learn how a novel approach with triple quadrupole mass spectrometry made it easier.

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Whiteboard video

Explore the Thermo Scientific LC-MS workflow solution for forensic toxicology that increases sample throughput and reduces cost per sample.