Triple Quadrupole GC-MS

The gold standard for high-throughput labs

The Thermo Scientific TSQ 9000 triple quadrupole GC-MS/MS system is the gold standard for the sensitive and specific quantitation of target compounds in high-throughput analytical laboratories. This system features multiple monitoring and scan modes as well as the triple off-axis Thermo Scientific DynaMax XR detection system. The system is equipped with either the Thermo Scientific TRACE 1300 or TRACE 1310 gas chromatograph.

Introducing the TSQ 9000 triple quadrupole GC-MS system

Laboratories performing food, environmental, or forensic toxicology testing demand analytical systems that are unstoppable in every way. That's the purpose of the TSQ 9000 GC-MS system.


The TSQ 9000 GC-MS/MS system delivers attogram-level sensitivity and best-in-class selected-reaction-monitoring (SRM) performance, so you consistently meet required detection limits for high capacity methods as you run samples.

Choose either the rugged Thermo Scientific ExtractaBrite ion source or the ultra-sensitive, ultra-robust Thermo Scientific Advanced Electron Ionization (AEI) source. Available in a dedicated system configuration, the AEI source provides highly efficient ionization and a more tightly focused ion beam to drive down instrument detection limits and reduce time-consuming sample concentration steps.

The Enhanced Velocity Optics Collision Cell (EvoCell) augments sensitivity and precision for complex methods. It can be used to increase the scope of SRM methods to fit a wider range of compounds and matrices, increase sample throughput by compressing GC time, or increase method resistance to matrix effects and retention time shifts.


Extended instrument uptime reduces turnaround time and overhead costs. The TSQ 9000 GC-MS/MS system is specifically designed for complex sample matrices in high-throughput applications. Whether you select the ExtractaBrite or AEI ion source, you benefit from high matrix tolerance to minimize maintenance.

With NeverVent technology for the ExtractaBrite source, it's possible to isolate the mass spectrometer from the gas chromatograph, allowing source cleaning, column replacement or injector maintenance, without downtime for venting. This boosts instrument productivity to unprecedented levels, meaning your time can be spent on producing quality results.


The TSQ 9000 GC-MS/MS system enhances the user experience, learning, and ease of switching from other platforms with automated software for tuning, method development, and targeted quantification workflows.

SIMBridge, AutoSRM, and t-SRM automate development and optimization of SRM-based targeted workflows, allowing even less-experienced users to develop MS/MS-based methods. Retention Time Alignment (RTA) adds an easy way to maintain retention times for high-throughput work. SmartTune simplifies instrument tuning, and if needed, informs the user of corrective actions, ensuring the system performs as required.


It's difficult to predict the challenges ahead. The fully scalable TSQ 9000 GC-MS/MS system provides a upgrade path from basic to advanced configurations, allowing you to add capability if you need it.


Pressure to increase productivity, and the growing list of compounds that laboratories must quantify and screen, necessitate workflow-driven software.

Intuitive Thermo Scientific Chromeleon Chromatography Data System (CDS) software is available to support quantitative workflows. Add Thermo Scientific eWorkflows to simplify creation of analytical sequences. If you need to jump-start method development, download ready-to-use eWorkflows from the Thermo Scientific AppsLab Library.

Add Thermo Scientific TraceFinder software and make targeted and untargeted analyses in food, environmental, and forensic toxicology applications simple, fast and productive. To simplify U.S. EPA-based environmental applications, the Environmental Analysis Extension Pack provides a set of predefined templates and GC-MS methods.

Talk to an expert about the power of UNSTOPPABLE triple quadrupole GC-MS/MS

Provide your contact information and we will have one of our experts contact you to answer any questions you may have about the UNSTOPPABLE TSQ 9000 triple quadrupole GC-MS/MS system.

Contact us

Unlike other systems, the TSQ 9000 GC-MS/MS system offers laboratories the opportunity to select best-in-class SRM performance, even for high capacity methods, while still benefiting from increased analytical robustness.

The TSQ 9000 GC-MS/MS system is uniquely placed to offer truly scalable performance that addresses increasingly challenging regulatory requirements, as well as providing effective ease-of-use tools to deliver consistent, class leading results, by both experienced and newer users.

CMD SchemaApp code