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Antibodies that detect Aquaporin 2 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry and Immunohistochemistry (Frozen). These antibodies target Aquaporin 2 in Human, Rat, Mouse, Ovine and Bovine samples. Our Aquaporin 2 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to Aquaporin 2. Find the Aquaporin 2 antibody that fits your needs. Choose from 1 of 27 Aquaporin 2 antibodies, which have been validated in experiments with 5 publications and 58 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
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Aquaporin 2 (AQP2) is a hormonally regulated water channel located in the renal collecting duct. Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans. A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells. Recently, serine-261 has been identified as a novel phosphorylation site on AQP2 and levels of phosphorylated S261 have been shown to decrease with vasopressin treatment suggesting its involvement in vasopressin-dependent AQP2 trafficking.
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
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