IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.
CD218 antigen-like family member A; CD218a; IL-18R-1; IL-18R1; IL-1Rrp; IL1 receptor-related protein; IL1R-rp; interleukin 1 receptor related protein; Interleukin-18 receptor 1
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