Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized.
ORP-4; OSBP-related protein 4; oxysterol binding protein-like 1; Oxysterol-binding protein 2; Oxysterol-binding protein-related protein 4
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