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The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels. Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis.
angiopoietin like 8; angiopoietin-like 8; angiopoietin-like protein 8; Angptl8; betatrophin; betatrophin variant 1; betatrophin variant 2; C19orf80; EG624219; Gm6484; hepatocellular carcinoma-associated gene TD26; hepatocellular carcinoma-associated protein TD26; hepatocellular carcinoma-associated protein TD26 homolog; lipasin; LOC100361444; predicted gene 6484; PRO1185; PVPA599; rCG31799-like; refeeding-induced fat and liver protein; Rifl; TD26; UNQ599/PRO1185
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