This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation.
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B-cell and monocyte-activating chemokine; BMAC; bolekine; BRAK; breast and kidney; C-X-C motif chemokine 14; chemokine (C-X-C motif) ligand 14; Chemokine BRAK; CXC chemokine in breast and kidney; KEC; Kidney-expressed chemokine CXC; member 14 (BRAK); MIP-2 gamma; MIP-2G; MIP2G; musculus CXC chemokine MIP-2gamma; NJAC; SCYB14; small inducible cytokine subfamily B (Cys-X-Cys); small inducible cytokine subfamily B (Cys-X-Cys), member 14; small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK); Small-inducible cytokine B14; tumor-suppressing chemokine