DUT Antibodies

Antibodies that detect DUT can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DUT in Human, Mouse and Rat samples. Our DUT polyclonal, recombinant monoclonal and... Antibodies that detect DUT can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DUT in Human, Mouse and Rat samples. Our DUT polyclonal, recombinant monoclonal and monoclonal antibodies are developed in... Antibodies that detect DUT can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DUT in Human, Mouse and Rat samples. Our DUT polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Knockdown and Relative expression to confirm specificity to DUT. Find the DUT antibody that fits your needs. Choose from 1 of 19 DUT antibodies, which have been validated in experiments with 4 publications and 58 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with... Antibodies that detect DUT can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target DUT in Human, Mouse and Rat samples. Our DUT polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Knockdown and Relative expression to confirm specificity to DUT. Find the DUT antibody that fits your needs. Choose from 1 of 19 DUT antibodies, which have been validated in experiments with 4 publications and 58 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.

Synonyms

5031412I06Rik; 5133400F09Rik; D2Bwg0749e; Deoxyuridine 5'-triphosphate nucleotidohydrolase; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; deoxyuridine triphosphatase; Dut; Dutp; dUTP diphosphatase; dUTP nucleotidohydrolase; dUTP pyrophosphatase; dUTPase; FLJ20622; PIP4; PPAR-interacting protein 4

DUT Antibodies

Target Information

Synonyms

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