JMJD2D Antibodies

Antibodies that detect JMJD2D can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target JMJD2D in Human, Non-human primate and Rat samples. Our JMJD2D polyclonal and... Antibodies that detect JMJD2D can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target JMJD2D in Human, Non-human primate and Rat samples. Our JMJD2D polyclonal and recombinant monoclonal... Antibodies that detect JMJD2D can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target JMJD2D in Human, Non-human primate and Rat samples. Our JMJD2D polyclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. Find the JMJD2D antibody that fits your needs. Choose from 1 of 13 JMJD2D antibodies, which have been validated in experiments with 1 publication and 20 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the... Antibodies that detect JMJD2D can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target JMJD2D in Human, Non-human primate and Rat samples. Our JMJD2D polyclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. Find the JMJD2D antibody that fits your needs. Choose from 1 of 13 JMJD2D antibodies, which have been validated in experiments with 1 publication and 20 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

The JMJD2D gene encodes a member of the Jumonji C domain-containing histone demethylases, which are involved in the epigenetic regulation of gene expression by demethylating lysine residues on histone proteins. JMJD2D specifically interacts with β-catenin and is implicated in colorectal cancer, where it activates transcription of target genes and promotes cell proliferation, migration, and tumor formation. Structurally, JMJD2D belongs to the JMJD2 family but exhibits distinct features, lacking certain regions that make it the most structurally divergent within the family. Additionally, JMJD2D stabilizes and cooperates with the hepatitis B virus protein HBx, facilitating cccDNA transcription by demethylating H3K9me3 and counteracting the repressive effects of p53. JMJD2D's role in various cellular processes highlights its importance in both cancer pathogenesis and viral replication, making it a potential target in therapeutic research for colorectal cancer and hepatitis B.

Synonyms

FLJ10251; JHDM3D; JmjC domain-containing histone demethylation protein 3D; JMJD2D; jumonji domain containing 2D; jumonji domain-containing protein 2D; KDM4D; lysine (K)-specific demethylase 4D; lysine demethylase 4D; lysine-specific demethylase 4D

JMJD2D Antibodies

Target Information

Synonyms

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