Anti-Progesterone Receptor Antibodies

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Progesterone Receptor Antibodies

Antibodies that detect Progesterone Receptor can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target Progesterone Receptor in Human, Mouse, Non-human primate, Rat and Feline samples. Our Progesterone Receptor monoclonal, polyclonal, recombinant monoclonal and cocktail antibodies are developed in Mouse, Rabbit and Rat. These antibodies have been verified by Relative Expression, Cell Treatment, IP-MS and Knockdown to confirm specificity to Progesterone Receptor. Find the Progesterone Receptor antibody that fits your needs. Choose from 1 of 136 Progesterone Receptor antibodies, which have been validated in experiments with 539 ... View more Antibodies that detect Progesterone Receptor can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target Progesterone Receptor in Human, Mouse, Non-human primate, Rat and Feline samples. Our Progesterone Receptor monoclonal, polyclonal, recombinant monoclonal and cocktail antibodies are developed in Mouse, Rabbit and Rat. These antibodies have been verified by Relative Expression, Cell Treatment, IP-MS and Knockdown to confirm specificity to Progesterone Receptor. Find the Progesterone Receptor antibody that fits your needs. Choose from 1 of 136 Progesterone Receptor antibodies, which have been validated in experiments with 539 publications and 445 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

The progesterone receptor (PR) is a member of the steroid family of nuclear receptors. The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites. PR-B is the transcriptionally active form and is responsible for activating genes for the maintenance of the endometrium, maintenance of pregnancy, and inhibition of ovulation. PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus. This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity. In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins. Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription. A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.

Synonyms

9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product

Target Video

6320267443112

Progesterone Receptor antibodies from Thermo Fisher Scientific

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Learn more about Progesterone Receptor primary antibodies that can be used in Western Blot, Immunohistochemistry, Immunocytochemistry and ELISA in Human, Rat, Mouse and Non-human primate samples.