Building a flow cytometry panel? Try Panel Builder
Antibodies that detect Progesterone Receptor can be used in several scientific applications, including Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target Progesterone Receptor in Human, Rat, Mouse, Non-human primate and Feline samples. Our Progesterone Receptor monoclonal, polyclonal, recombinant monoclonal and cocktail antibodies are developed in Mouse, Rabbit and Rat. These antibodies have been verified by Relative expression, Cell treatment, IP-MS and Knockdown to confirm specificity to Progesterone Receptor. Find the Progesterone Receptor antibody that fits your needs. Choose from 1 of 134 Progesterone Receptor antibodies, which have been validated in experiments with 525 publications and 435 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
View more
The progesterone receptor (PR) is a member of the steroid family of nuclear receptors. The PR mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. PR is found as a 94 kDa protein (Form A) or a 120 kDa protein (Form B) due to the use of alternative translation initiation sites. PR-B is the transcriptionally active form and is responsible for activating genes for the maintenance of the endometrium, maintenance of pregnancy, and inhibition of ovulation. PR-A is identical to PR-B except for a 165 amino acid deletion at the N-terminus. This deletion exposes a 140 amino acid inhibitory domain (ID) that acts as a repressor of steroid hormone transcriptional activity. In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins. Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription. A Null mutation in the PGR gene leads to pleiotrophic reproductive abnormalities.
9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
100 µg
100 µg
500 µL
100 µL
100 µg
500 µL
100 µg
500 µL
500 µL
500 µL
100 µL
500 µL
200 µg
100 µL
100 µL
100 µL
500 µL
100 µg
100 µL
100 µL
500 µL
100 µg
100 µg
100 µL
100 µg
150 µL
100 µL
100 µL
100 µL
100 µL
100 µL
100 µL
100 µg
100 µL
100 µg
100 µg
100 µg
100 µg
100 µL
100 µL
100 µL
100 µL
100 µL
100 µL
100 µL
100 µL
Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.
More than 18,000 custom antibodies created so far.
Talk to a specialist now
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support
