Anti-SHARPIN Antibodies

SHARPIN Antibodies

Antibodies that detect SHARPIN can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target SHARPIN in Human, Rat, Mouse and Canine samples. Our SHARPIN polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown and Relative Expression to confirm specificity to SHARPIN. Find the SHARPIN antibody that fits your needs. Choose from 1 of 19 SHARPIN antibodies, which have been validated in experiments with 42 publications and 48 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ... View more Antibodies that detect SHARPIN can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target SHARPIN in Human, Rat, Mouse and Canine samples. Our SHARPIN polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown and Relative Expression to confirm specificity to SHARPIN. Find the SHARPIN antibody that fits your needs. Choose from 1 of 19 SHARPIN antibodies, which have been validated in experiments with 42 publications and 48 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.

Synonyms

0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1

SHARPIN Antibodies

Target Information

Synonyms

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