Anti-SMAD2 Antibodies

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SMAD2 Antibodies

Antibodies that detect SMAD2 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target SMAD2 in Human, Mouse, Rat, Non-human primate and Mink samples. Our SMAD2 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell Treatment, Knockdown and Relative Expression to confirm specificity to SMAD2. Find the SMAD2 antibody that fits your needs. Choose from 1 of 53 SMAD2 antibodies, which have been validated in experiments with 196 publications and 259 images featured in ... View more Antibodies that detect SMAD2 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target SMAD2 in Human, Mouse, Rat, Non-human primate and Mink samples. Our SMAD2 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell Treatment, Knockdown and Relative Expression to confirm specificity to SMAD2. Find the SMAD2 antibody that fits your needs. Choose from 1 of 53 SMAD2 antibodies, which have been validated in experiments with 196 publications and 259 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling. Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin. In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.

Synonyms

7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Target Video

6320272291112

SMAD2 antibodies from Thermo Fisher Scientific

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Learn more about SMAD2 primary antibodies that can be used in Western Blot, Immunocytochemistry, Immunohistochemistry and ELISA in Human, Mouse, Rat and Non-human primate samples.