TPMT Antibodies

Antibodies that detect TPMT can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target TPMT in Human, Mouse, Rat and Canine samples. Our TPMT monoclonal, polyclonal and recombinant... Antibodies that detect TPMT can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target TPMT in Human, Mouse, Rat and Canine samples. Our TPMT monoclonal, polyclonal and recombinant monoclonal antibodies are... Antibodies that detect TPMT can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target TPMT in Human, Mouse, Rat and Canine samples. Our TPMT monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the TPMT antibody that fits your needs. Choose from 1 of 26 TPMT antibodies, which have been validated in experiments with 1 publication and 92 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the... Antibodies that detect TPMT can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target TPMT in Human, Mouse, Rat and Canine samples. Our TPMT monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the TPMT antibody that fits your needs. Choose from 1 of 26 TPMT antibodies, which have been validated in experiments with 1 publication and 92 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine. Defects in TPMT are the cause of thiopurine S-methyltransferase deficiency (TPMT deficiency). TPMT is an enzyme involved in the normal metabolic inactivation of thiopurine drugs. These drugs are generally used as immunosupressants or cytotoxic drugs and are prescribed for a variety of clinical conditions including leukemia, autoimmune disease and organ transplantation. Patients with intermediate or no TPMT activity are at risk of toxicity after receiving standard doses of thiopurine drugs and it is shown that inter-individual differences in response to these drugs are largely determined by genetic variation at the TPMT locus.

Synonyms

AW106912; HGNC:12014; S-adenosyl-L-methionine:thiopurine S-methyltransferase; thiopurine methyltransferase; Thiopurine S-methyltransferase; TPMT; TPMTD; truncated thiopurine methyltransferase

TPMT Antibodies

Target Information

Synonyms

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