TSP50 Antibodies

Antibodies that detect TSP50 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target TSP50 in Human and Mouse samples. Our TSP50 polyclonal and monoclonal antibodies are... Antibodies that detect TSP50 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target TSP50 in Human and Mouse samples. Our TSP50 polyclonal and monoclonal antibodies are developed in Rabbit, Rat,... Antibodies that detect TSP50 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target TSP50 in Human and Mouse samples. Our TSP50 polyclonal and monoclonal antibodies are developed in Rabbit, Rat, Goat and Mouse. Find the TSP50 antibody that fits your needs. Choose from 1 of 10 TSP50 antibodies, which have been validated in experiments with 8 publications and 17 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot... Antibodies that detect TSP50 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target TSP50 in Human and Mouse samples. Our TSP50 polyclonal and monoclonal antibodies are developed in Rabbit, Rat, Goat and Mouse. Find the TSP50 antibody that fits your needs. Choose from 1 of 10 TSP50 antibodies, which have been validated in experiments with 8 publications and 17 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Testes-specific protease 50 (TSP50) is a gene located within the chromosome region 3p21.31, primarily expressed in testicular tissue, and is homologous to serine proteases. However, TSP50 contains a distinctive catalytic triad where serine, a crucial catalytic residue, is replaced by threonine, allowing it to exhibit a novel protease activity. TSP50 is recognized for its role as a pro-oncogene, contributing significantly to cancer progression by promoting aerobic glycolysis, known as the Warburg effect, in hepatocellular carcinoma cells through interaction with pyruvate kinase M2 isoform (PKM2). This function underlines its involvement in cancer metabolism, as it attenuates colitis by regulating TGF-ß signaling pathways. Furthermore, studies have linked TSP50 to cancer stem cell maintenance, driving stem-like properties in breast cancer cells, thereby facilitating tumor initiation and self-renewal capabilities. These characteristics highlight TSP50's potential as a target in therapeutic interventions for cancer treatment.

Synonyms

79H19C; Cancer/testis antigen 20; CT20; Probable threonine protease PRSS50; protease, serine 50; protease, serine, 50; PRSS50; Serine protease 50; testes specific protease 50; testes-specific protease 50; testicular tissue protein Li 210; testis-specific protease-like protein 50; Tsp50

TSP50 Antibodies

Target Information

Synonyms

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